BDBM50622555 CHEMBL5410724

SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCN1CCCC1)N(C)C(=O)C=C

InChI Key InChIKey=GHCDVBSKNGUGCK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50622555   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 5nMAssay Description:Inhibition of GLP (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MLL1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MLL4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622555(CHEMBL5410724)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed