BDBM50622536 CHEMBL5403426

SMILES CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c1cccc2O

InChI Key InChIKey=PDXPGFKIBOLVGG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50622536   

TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 27nMAssay Description:Displacement of AVPI-biotin from human XIAP BIR3 domain (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS cells preincubated f...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 17nMAssay Description:Displacement of AVPI-biotin from cIAP1 BIR3 domain (unknown origin) preincubated for 6 hrs followed by AVPI-biotin addition for 2 hrs by DELFIAMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 8.40nMAssay Description:Displacement of AVPI-biotin from cIAP2 BIR3 domain (unknown origin) preincubated for 6 hrs followed by AVPI-biotin addition for 2 hrs by DELFIAMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 25nMAssay Description:Displacement of AVPI-biotin from human XIAP BIR3 domain (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS cells incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 19nMAssay Description:Displacement of AVPI-biotin from cIAP1 BIR3 domain (unknown origin) incubated for 2 hrs by DELFIAMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50622536(CHEMBL5403426)
Affinity DataIC50: 10nMAssay Description:Displacement of AVPI-biotin from cIAP2 BIR3 domain (unknown origin) incubated for 2 hrs by DELFIAMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed