BDBM50622320 CHEMBL5437385

SMILES Fc1ccc(NS(=O)(=O)c2ccccc2)c(F)c1-n1cc(nn1)-c1cnc2[nH]nc(OC3CCN(C3)C(=O)C=C)c2c1

InChI Key InChIKey=PPILDDFMLSKYDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622320   

TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622320(CHEMBL5437385)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622320(CHEMBL5437385)
Affinity DataIC50: 247nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin) incubated for 1 hr in presence of ATP by envision multilabel reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed