BDBM50622285 CHEMBL5401398

SMILES CCN(C1CCOCC1)c1cc(CNC(=O)C=C)cc(C(=O)NCc2c(SC)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=BKTRXKQBQKZJJS-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50622285   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT4 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NSD1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NSD2 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL1 (unknown origin) using histone peptide/SAM as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL4 (unknown origin) using histone peptide/SAM as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLP (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed