BDBM50622189 CHEMBL5417945

SMILES CN(Cc1ccccc1)c1ncnc2[nH]c(cc12)-c1cccc(O)c1

InChI Key InChIKey=XMEPCGHGLWNLNM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622189   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622189(CHEMBL5417945)
Affinity DataKd:  72nMAssay Description:Binding affinity to autoinhibited CSF1R (538 to 939) (unknown origin) expressed in Escherichia coli BL21 strain assessed as dissociation constant inc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622189(CHEMBL5417945)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to non-autoinhibited CSF1R (564 to 939) (unknown origin) expressed in Escherichia coli BL21 strain assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622189(CHEMBL5417945)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed