BDBM50622114 CHEMBL5398468

SMILES CCCC(=O)N1CCC(CC1)Nc1c(cnc2[nH]ccc12)-c1cn[nH]c1

InChI Key InChIKey=UWAWQDDCHUKHDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622114   

TargetTyrosine-protein kinase JAK1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50622114(CHEMBL5398468)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50622114(CHEMBL5398468)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed