BDBM50622039 CHEMBL5400739

SMILES OC(=O)c1ccc(CCOc2c(F)ccc3nc([nH]c(=O)c23)C(=O)NCc2cccc(O)c2)cc1

InChI Key InChIKey=UZAJXMPARRSZBZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50622039   

Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetStromelysin-2(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant MMP-10 using Mca-Aug-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed