BDBM50621952 CHEMBL5417219

SMILES CCN(CC)CCn1ncc2cc(Nc3nccc(n3)-c3cn(c4ccccc34)S(=O)(=O)CC)cc(NC(=O)C3CC3)c12

InChI Key InChIKey=AFMFMUZIPUTSGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621952   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621952(CHEMBL5417219)
Affinity DataIC50: 26nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed