BDBM50621948 CHEMBL5402235

SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6]-[#6]-n1ncc2cc(-[#7]-c3nccc(n3)-c3cn(c4ccccc34)S(=O)(=O)[#6]-[#6])cc(-[#7]-[#6](=O)\[#6]=[#6](\[#6])-[#6])c12

InChI Key InChIKey=OVNQKFMYKCWUKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621948   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621948(CHEMBL5402235)
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed