BDBM50621940 CHEMBL5436545

SMILES [#6]-[#6]S(=O)(=O)n1cc(-c2ccnc(-[#7]-c3cc(-[#7]-[#6](=O)\[#6]=[#6](/[#6])-[#6])c4n(-[#6]-[#6]-[#7](-[#6])-[#6])ncc4c3)n2)c2ccccc12

InChI Key InChIKey=LWNBMGGRORFXHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621940   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621940(CHEMBL5436545)
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed