BDBM50621845 CHEMBL5408410

SMILES CN(C(=O)CSc1nc(C)c(Cl)c(C)c1C#N)c1ccccc1

InChI Key InChIKey=RMTRDJCQYPWYTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621845   

TargetDNA polymerase theta(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50621845(CHEMBL5408410)
Affinity DataIC50: 200nMAssay Description:Inhibition of POLQ PD (unknown origin) (1819 to 2590 residues) incubated for 15 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDNA polymerase theta(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50621845(CHEMBL5408410)
Affinity DataIC50: 200nMAssay Description:Inhibition of POLQ PD (unknown origin) (1819 to 2590 residues) incubated for 15 mins by luminescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed