BDBM50621816 CHEMBL5425753

SMILES CCN(CC)C(=O)c1ccc2n(CCC(C)C)c(Cc3ccc(OC(=O)NCc4ccccc4)cc3)nc2c1

InChI Key InChIKey=YEDMNOZIAFUYSZ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621816   

TargetCholinesterase(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50621816(CHEMBL5425753)
Affinity DataIC50: 190nMAssay Description:Pseudo-irreversible inhibition of human BChE using butyrylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition by Ell...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50621816(CHEMBL5425753)
Affinity DataIC50: 4.50E+3nMAssay Description:Pseudo-irreversible inhibition of human AChE using acetylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition by Ellm...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50621816(CHEMBL5425753)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membrane incubated for 3 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50621816(CHEMBL5425753)
Affinity DataEC50:  7.71E+3nMAssay Description:Agonist activity at human CB2 receptor stably expressed in CHO-K1 cells co-expressing Galphaq16 by Fluo-4AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed