BDBM50621803 CHEMBL5426953

SMILES FC(F)(F)C1(N=N1)c1ccc(CN(CCOCCOc2ccc(cc2)-c2cc(=O)c3ccccc3o2)Cc2ccc(cc2)C2(N=N2)C(F)(F)F)cc1

InChI Key InChIKey=GWTMSPKGWFNRHT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621803   

TargetATP-dependent translocase ABCB1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50621803(CHEMBL5426953)
Affinity DataIC50: 158nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50621803(CHEMBL5426953)
Affinity DataEC50:  3.01E+3nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated paclitaxel resistance...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed