BDBM50621783 CHEMBL5419544

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1cccc(c1)C1(CC1)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=GNGVDMYJKXLTKW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621783   

TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621783(CHEMBL5419544)
Affinity DataEC50:  122nMAssay Description:Agonist activity at FXR-LBD (unknown origin) using fluorescein-coactivator peptide incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621783(CHEMBL5419544)
Affinity DataEC50:  580nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed