BDBM50621762 CHEMBL5411250

SMILES OC(=O)c1ccc(cc1)-c1ccc(OCc2c(onc2-c2ccccc2OC(F)(F)F)C2CC2)cc1

InChI Key InChIKey=QMWHPJKMIFTOFS-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621762   

TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621762BDBM50621762(CHEMBL5411250)
Affinity DataEC50:  781nMAssay Description:Agonist activity at FXR-LBD (unknown origin) incubated for 3 hrs in presence of fluorescein-coactivator peptide by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621762BDBM50621762(CHEMBL5411250)
Affinity DataEC50:  781nMAssay Description:Agonist activity at FXR-LBD (unknown origin) using fluorescein-coactivator peptide incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621762BDBM50621762(CHEMBL5411250)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of HSD17B13 (unknown origin) using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based lum...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed