BDBM50621756 CHEMBL5439051

SMILES CC(C)(Oc1ccc(cc1)-c1ccc(OCc2c(noc2C2CC2)-c2c(Cl)cccc2Cl)cc1)C(O)=O

InChI Key InChIKey=VMTYJQKZZUYIGU-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621756   

TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621756(CHEMBL5439051)
Affinity DataEC50:  261nMAssay Description:Agonist activity at FXR-LBD (unknown origin) using fluorescein-coactivator peptide incubated for 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621756(CHEMBL5439051)
Affinity DataEC50:  3.22E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetFatty acid-binding protein, liver(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621756(CHEMBL5439051)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from FABP1 (unknown origin) incubated for 3 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed