BDBM50621641 CHEMBL5410162

SMILES COc1cc2c(NCc3c(C)cc(C)[nH]c3=O)nc(nc2cc1OCCCN1CCCC1)N1CCC(F)(F)CC1

InChI Key InChIKey=CVWPNABDQLFDLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621641   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621641(CHEMBL5410162)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human EZH2 using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50621641(CHEMBL5410162)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant EHMT2 G9a using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed