BDBM50621626 CHEMBL5421919

SMILES C[C@](O)(Cn1cc(F)c2ccccc12)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=SFWNEEFKVCGGMU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621626   

TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50621626(CHEMBL5421919)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at CMV-tagged full length wild type human AR expressed in HEK293 cells co-transfected with GRE-LUC and CMV-renilla LUC assessed a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50621626(CHEMBL5421919)
Affinity DataKi:  332nMAssay Description:Displacement of [3H]mibolerone from GST-tagged wild type AR ligand binding domain (unknown origin) incubated for 16 hrs by scintillation counting ana...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed