BDBM50621618 CHEMBL5426016

SMILES C[C@](O)(Cn1nc(Cl)c2cc(F)ccc12)C(=O)Nc1cnc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=JVQWDYJXNUOECS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621618   

TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50621618(CHEMBL5426016)
Affinity DataIC50: 183nMAssay Description:Antagonist activity at CMV-tagged full length wild type human AR expressed in HEK293 cells co-transfected with GRE-LUC and CMV-renilla LUC assessed a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50621618(CHEMBL5426016)
Affinity DataIC50: 242nMAssay Description:Antagonist activity at AR F876L mutant (unknown origin) expressed in COS cells co-transfected with GRE-LUC and CMV-renilla LUC assessed as inhibition...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50621618(CHEMBL5426016)
Affinity DataKi:  3.01E+3nMAssay Description:Displacement of [3H]mibolerone from GST-tagged wild type AR ligand binding domain (unknown origin) incubated for 16 hrs by scintillation counting ana...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed