BDBM50621578 CHEMBL5407694

SMILES O=S1(=O)C=C(C2CC2)c2cc3nccc(Nc4ccc5scnc5c4)c3cc12

InChI Key InChIKey=GFRNPKPFXYAEBM-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621578   

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50621578(CHEMBL5407694)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human RIPK3 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50621578(CHEMBL5407694)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human RIPK3 using MBP as substrate preincubated for 15 mins followed by substrate addition and measured after 2 hrs by ADP-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50621578(CHEMBL5407694)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed