BDBM50621572 CHEMBL5094279

SMILES CNc1ccc2ccc(OCc3cncc(c3)-n3cc([C@@H]4CCCO4)c4c(N)ncnc34)cc2n1

InChI Key InChIKey=ADJINURAZZCEQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621572   

TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50621572(CHEMBL5094279)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50621572(CHEMBL5094279)
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) using biotinylated RNA (UCUGGACUAAA-biotin) and 3H-SAM as substrate preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed