BDBM50621474 CHEMBL5425561

SMILES COc1cc2CCn3cc(\C=N\c4ccc(cc4)\N=C\c4cn5CCc6cc(OC)c(OC)cc6-c5c4-c4ccc(Cl)cc4)c(c3-c2cc1OC)-c1ccc(Cl)cc1

InChI Key InChIKey=IKAVVQHSMHYMDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621474   

TargetAcetylcholinesterase(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50621474(CHEMBL5425561)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant AChE incubated for 20 mins by Ellmans methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50621474(CHEMBL5425561)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of amyloid beta 40 (unknown origin) aggregation for 2 hrs by ThT fluoroscence assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed