BDBM50621453 CHEMBL5408201

SMILES [O-][N+](=O)c1ccc2nc(sc2c1)C(=O)NCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=JTJQWNKGAGILHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621453   

TargetAcetylcholinesterase(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50621453(CHEMBL5408201)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant AChE preincubated for 5 mins followed by substrate addition measured every 2 mins by Ellmans methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50621453(CHEMBL5408201)
Affinity DataIC50: 4.66E+6nMAssay Description:Inhibition of human recombinant BChE by Ellmans method preincubated for 5 mins followed by substrate addition measured every 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50621453(CHEMBL5408201)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of amyloid beta 42 (unknown origin) self aggregation incubated for 48 hrs by fluoroMax-4 spectrofluorometeric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed