BDBM50621433 CHEMBL5399395

SMILES OC(=O)CCc1cc(Cl)c(Oc2ccsc2C(=O)N2CCN(C3CC3)c3ccccc23)cc1Cl

InChI Key InChIKey=DNNQBMCCWKUMNJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621433   

TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataEC50:  11nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed