BDBM50621377 CHEMBL5419541

SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=PURIVPGRKIUWCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621377   

TargetCasein kinase I isoform delta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50621377(CHEMBL5419541)
Affinity DataIC50: 17nMAssay Description:Displacement of kinase tracer 8 from NanoLuc-tagged CK1 delta (unknown origin) transfected in CHO cells by BRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCasein kinase I isoform delta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50621377(CHEMBL5419541)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human CK1 delta expressed in Escherichia coli BL21 cells using PLSRTL-pS-VA-pS-LPGL as substrate meas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50621377(CHEMBL5419541)
Affinity DataIC50: 140nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 11(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50621377(CHEMBL5419541)
Affinity DataIC50: 250nMAssay Description:Inhibition of p38 beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed