BDBM50621325 CHEMBL5420340

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(CC1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=LHWNFQORZAPTFK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621325   

TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50621325(CHEMBL5420340)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human human carbonic anhydrase II assessed as inhibition constant incubated for 15 min by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50621325(CHEMBL5420340)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human human carbonic anhydrase IX assessed as inhibition constant incubated for 15 min by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50621325(CHEMBL5420340)
Affinity DataKi:  5.70nMAssay Description:Inhibition of human carbonic anhydrase I assessed as inhibition constant incubated for 15 min by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50621325(CHEMBL5420340)
Affinity DataKi:  52nMAssay Description:Inhibition of human human carbonic anhydrase XII assessed as inhibition constant incubated for 15 min by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed