BDBM50621293 CHEMBL5439266

SMILES C[C@H]1OC(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)\C(C)=C/C[C@H](O)[C@@H]1C

InChI Key InChIKey=ONEKFAPECJXSTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621293   

TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621293(CHEMBL5439266)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50621293(CHEMBL5439266)
Affinity DataIC50: 64nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed