BDBM50621126 CHEMBL5407312::US20250162994, Example 11

SMILES ONC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1

InChI Key InChIKey=UMCMUHXVQOVKIH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50621126   

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal human recombinant LSD1More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 290nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Ligand InfoSimilars
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 5.40E+5nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 540nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50621126(CHEMBL5407312 | US20250162994, Example 11)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed