BDBM50620657 CHEMBL5440445

SMILES COc1ccc2sc3c(C)ccc(NCCC4CCN(C)CC4)c3c(=O)c2c1

InChI Key InChIKey=RGJSERYMQYYVAH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50620657   

TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 960nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed