BDBM50620518 CHEMBL5431805

SMILES C[C@H]1COCCN1c1cc(N2CCOC[C@H]2C)c2nc([nH]c2n1)-c1cc[nH]n1

InChI Key InChIKey=LXQPWBFVIIXOMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50620518   

TargetSerine/threonine-protein kinase mTOR(Mouse)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50620518(CHEMBL5431805)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of mTOR in TSC1 knockout mouse MEF cells assessed as reduction in phosphorylated S6 level at serine 240/244 residues incubated for 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50620518(CHEMBL5431805)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ATR (unknown origin)-driven CHK1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50620518(CHEMBL5431805)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed