BDBM50620473 CHEMBL5438846

SMILES OC(=O)c1cc(-c2ccc(cc2)C2=CC3(CNC3)C2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MCHDJAGBMLLHOF-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50620473   

TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataIC50: 9.70nMAssay Description:Displacement of fluorescent tracer 4-(4-(1-(4-(1-(6-(3-carboxylato-4-(3-iminio-3H-xanthen-9-yl)benzamido)hexyl)-4,5-dihydro-1H-pyrrol-3-yl)butyl)pipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataIC50: 16nMAssay Description:Displacement of fluorescent tracer 4-(4-(1-(4-(1-(6-(3-carboxylato-4-(3-iminio-3H-xanthen-9-yl)benzamido)hexyl)-4,5-dihydro-1H-pyrrol-3-yl)butyl)pipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  5.60nMAssay Description:Displacement of fluorescent tracer 4-(4-(1-(4-(1-(6-(3-carboxylato-4-(3-iminio-3H-xanthen-9-yl)benzamido)hexyl)-4,5-dihydro-1H-pyrrol-3-yl)butyl)pipe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]-DTG from human sigma 2 receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]-Ketanserin from human muscarinic M5 receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [3H]-Pyrilamine from human histamine H1 receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  6.70E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT1B receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBeta-3 adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  6.80E+3nMAssay Description:Displacement of [125I]-Pindolol from human adrenergic beta3 receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50620473(CHEMBL5438846)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]-Prazosin from human adrenergic alpha1B receptor assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed