BDBM50620388 CHEMBL5420881

SMILES Cc1ccccc1OCC(=O)Nc1cc(cn(C)c1=O)C(=O)N1CCCC1

InChI Key InChIKey=HDESYZHTQAEDLX-UHFFFAOYSA-N

Data  1 KI  1 Kd  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50620388   

TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataKd:  31nMAssay Description:Displacement of K22-[TAMRA]-Nle-17,30-PP from human Nluc-Y4R transfected with COS-7 cells assessed as dissociation constant of K22-[TAMRA]-Nle-17,30-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  48nMAssay Description:Positive allosteric modulation of YFP tagged human Y1 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of YFP tagged human Y2 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  31nMAssay Description:Positive allosteric modulation of YFP tagged human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  1.90nMAssay Description:Positive allosteric modulation of YFP tagged human Y5 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Mouse)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  0.0700nMAssay Description:Positive allosteric modulation of mouse Y4 receptor transfected with COS-7 cells assessed as activation of G-protein signaling measured after 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Rat)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  0.310nMAssay Description:Positive allosteric modulation of rat Y4 receptor transfected with COS-7 cells assessed as activation of G-protein signaling measured after 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataKi:  4.40nMAssay Description:Displacement of K22-[TAMRA]-Nle-17,30-PP from human Nluc-tagged Y4R transfected with COS-7 cells assessed as inhibition constant of pancreatic polype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed