BDBM50620381 CHEMBL5395369

SMILES [H][C@]12C[C@]3([H])C[C@]([H])(C1)CC(CNC(=O)Nc1ccc4n(Cc5ccc(cc5)C(=O)OC)ccc4c1)(C2)C3

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50620381   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620381(CHEMBL5395369)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620381(CHEMBL5395369)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed