BDBM50620080 CHEMBL5423619

SMILES [H][C@@]1(C[C@H](NC(=O)[C@H](CC2CC2)NC(=O)OCc2ccccc2)\C=C\C(C)=O)CCNC1=O

InChI Key InChIKey=RMKKWIQMBAQCJI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50620080   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50620080(CHEMBL5423619)
Affinity DataKi:  252nMAssay Description:Inhibition of SARS-CoV-2 MPro using Dabcyl-KTSAVLQSGFRKME-Edans as substrate assessed as inhibition constant measured for 10 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50620080(CHEMBL5423619)
Affinity DataKi:  3.38E+3nMAssay Description:Inhibition of human Cathepsin L using Cbz-Phe-Arg-AMC as substrate assessed as inhibition constant measured for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50620080(CHEMBL5423619)
Affinity DataKi:  7.88E+3nMAssay Description:Inhibition of human Cathepsin B using Cbz-Phe-Arg-7-amino-4-methylcoumarin as substrate assessed as inhibition constant measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed