BDBM50620059 CHEMBL5432925

SMILES Fc1ccc(cc1)S(=O)(=O)Oc1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50620059   

LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 740nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAutotaxin(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human NPP2 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 330nMAssay Description:Inhibition of Carbonic anhydrase 9 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 680nMAssay Description:Inhibition of Carbonic anhydrase 12 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed