BDBM50619827 CHEMBL5440893

SMILES Fc1ccc(F)c(Sc2c(C3CC3)c(=O)[nH]c(=O)n2COCc2ccccc2)c1

InChI Key InChIKey=FAPXJUPETHRJJI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50619827   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase assessed as inhibition of biotin deoxyuridine triphosphate incorporation into proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4M (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619827(CHEMBL5440893)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG potassium channel expressed in CHO cells by manual patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed