BDBM50619822 CHEMBL5405063::US20240317663, Compound epi-IX

SMILES [#6]-[#6](-[#6])-[#6@H]-1-[#6]-[#6@H](-[#6@H](-[#6])\[#6](-[#6]-1)=[#6]\[#6]=[#6]-1/[#6]-[#6@@H](-[#8])-[#6]-[#6@H](-[#8])-[#6]-1)-c1cccc(-[#8]-[#6]-[#6]C([#6])([#6])[#8])c1

InChI Key InChIKey=CFQMEDLIFWVAQL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50619822   

TargetVitamin D3 receptor(Human)
Kanagawa University

Curated by ChEMBL
LigandPNGBDBM50619822(US20240317663, Compound epi-IX | CHEMBL5405063)
Affinity DataEC50:  846nMAssay Description:Agonist activity at Vitamin D receptor (unknown origin) assessed as increase in fluorescein labeled TRAP220/DRIP-2 coactivator peptide requirement by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetVitamin D3 receptor(Human)
Kanagawa University

Curated by ChEMBL
LigandPNGBDBM50619822(US20240317663, Compound epi-IX | CHEMBL5405063)
Affinity DataEC50:  846nMAssay Description:A VDR ligand binding domain tagged with GST (VDR-LBD(GST)), a fluorescein-TRAP220/DRIP-2-bound coactivator peptide (Fluorescein-peptide), LanthaScree...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent