BDBM50619625 CHEMBL5196318

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCn2cc(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)\C=C\CN3CCCCC3)nn2)C(C)(C)C)cc1

InChI Key InChIKey=RBUUUIFZYMVDPT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619625   

TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619625(CHEMBL5196318)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR del19 mutant in human HCC827 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619625(CHEMBL5196318)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR in human NCI-H1975 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619625(CHEMBL5196318)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of wild type EGFR in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50619625(CHEMBL5196318)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of wild type EGFR in human A-431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed