BDBM50619501 4-(4-hydroxybenzylidene) curcumin::CHEMBL260079

SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](=O)-[#6](=[#6]/c2ccc(-[#8])cc2)\[#6](=O)\[#6]=[#6]\c2ccc(-[#8])c(-[#8]-[#6])c2)ccc1-[#8]

InChI Key InChIKey=PVPLSZWXTGWUKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619501   

TargetAlpha-synuclein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50619501(CHEMBL260079 | 4-(4-hydroxybenzylidene) curcumin)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of alpha-Synuclein (unknown origin) aggregation incubated for 72 hrs by ThT-based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed