BDBM50619399 CHEMBL5404334

SMILES CNC(=O)c1cc(cc(c1N[C@@H]2CCCC[C@@H]2NC(=O)c3cncc4c3cccc4)N(=O)=O)Br

InChI Key InChIKey=BPLNOSFMIIASSJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619399   

TargetReplicase polyprotein 1ab(2019-nCoV)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50619399(CHEMBL5404334)
Affinity DataEC50:  36nMAssay Description:Inhibition of SARS-CoV-2 Main protease expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by affinity chromatography methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50619399(CHEMBL5404334)
Affinity DataIC50: 990nMAssay Description:Inhibition of SARS-CoV-2 PLproMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50619399(CHEMBL5404334)
Affinity DataIC50: 120nMAssay Description:Inhibition of SARS-CoV-2 MPro using Dabcyl-KTSAVLQSGFRKME-Edans as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Qufu Normal University

Curated by ChEMBL
LigandPNGBDBM50619399(CHEMBL5404334)
Affinity DataIC50: 72nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed