BDBM50619289 CHEMBL5412612

SMILES Fc1cc(ccc1C(F)(F)F)-c1cncc(c1)C1OCCO1

InChI Key InChIKey=NCWBQORETDKWPL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619289   

TargetCytochrome P450 11B1, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619289(CHEMBL5412612)
Affinity DataIC50: 441nMAssay Description:Inhibition of human CYP11B1 stably transfected in mouse Y-1 cells using deoxycortisol or deoxycorticosterone as substrate incubated for 48 hrs by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619289(CHEMBL5412612)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CYP11B2 stably transfected in mouse Y-1 cells using deoxycortisol or deoxycorticosterone as substrate incubated for 48 hrs by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619289(CHEMBL5412612)
Affinity DataIC50: 157nMAssay Description:Inhibition of human CYP11B1 expressed in human NCI-H295 cells incubated for 48 hrs by radioimmuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619289(CHEMBL5412612)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human CYP11B2 expressed in human NCI-H295 cells incubated for 48 hrs by radioimmuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed