BDBM50619271 CHEMBL5413659

SMILES Cc1cncc(c1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=TWEJBFSXYBSODY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619271   

TargetCytochrome P450 11B1, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619271(CHEMBL5413659)
Affinity DataIC50: 169nMAssay Description:Inhibition of human CYP11B1 stably transfected in mouse Y-1 cells using deoxycortisol or deoxycorticosterone as substrate incubated for 48 hrs by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619271(CHEMBL5413659)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human CYP11B2 stably transfected in mouse Y-1 cells using deoxycortisol or deoxycorticosterone as substrate incubated for 48 hrs by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619271(CHEMBL5413659)
Affinity DataIC50: 48nMAssay Description:Inhibition of human CYP11B1 expressed in human NCI-H295 cells incubated for 48 hrs by radioimmuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University Hospital of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50619271(CHEMBL5413659)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human CYP11B2 expressed in human NCI-H295 cells incubated for 48 hrs by radioimmuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed