BDBM50619190 CHEMBL5420439

SMILES ClCC(=O)NCCSc1ccc(Cl)cc1

InChI Key InChIKey=DWJLPYPCRJRTDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619190   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619190(CHEMBL5420439)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619190(CHEMBL5420439)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibition of TEAD1 (209 to 426 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619190(CHEMBL5420439)
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed