BDBM50619189 CHEMBL5429883

SMILES NC(=O)c1oc2ccccc2c1NC(=O)CCl

InChI Key InChIKey=JGIYBKFOIUVCQB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619189   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619189(CHEMBL5429883)
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619189(CHEMBL5429883)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619189(CHEMBL5429883)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of TEAD1 (209 to 426 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619189(CHEMBL5429883)
Affinity DataIC50: 2.54E+5nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed