BDBM50619093 CHEMBL5412738

SMILES CC(C)[C@H]1CC[C@H](CC1)N1CCC(CC1)n1c(CNC(C)=O)cc2ccccc12

InChI Key InChIKey=VEFKNVILUVRTOC-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50619093   

TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human NOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataEC50:  112nMAssay Description:Agonist activity at human MOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human DOP expressed in CHO cells membrane assessed as increase in [35S]GTPgammaS binding incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]N/OFQ from human NOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-DAMGO from human MOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DPDPE from human DOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50619093(CHEMBL5412738)
Affinity DataKi:  176nMAssay Description:Displacement of [3H]-U69593 from human KOP expressed in CHO cells membrane incubated for 60 mins by beta liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed