BDBM50619065 CHEMBL5412877

SMILES COc1ccc(c(OC)n1)-c1ccc2c(C)cc(=O)n(C)c2c1

InChI Key InChIKey=NFFBUIFLOKMWKQ-UHFFFAOYSA-N

Data  2 KI  4 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50619065   

TargetBromodomain-containing protein 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataKd:  340nMAssay Description:Binding affinity to human partial length BRD7 bromodomain (125 to 254 residues) expressed in mammalian expression system by BROMOscan KdELECT analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataIC50: 5.40E+3nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD7 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataIC50: 3.00E+5nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD9 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to N-terminal His TEV-tagged human recombinant BRD7 bromodomain expressed in Escherichia coli BL21(DE3) by microscale thermophoresis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataKd:  655nMAssay Description:Binding affinity to human partial length BRD9 bromodomain (130 to 259 residues) expressed in bacterial expression system by BROMOscan KdELECT analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of NanoBRET BRD Tracer-02 from Nanoluc-fused BRD7 bromodomain (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of NanoBRET BRD Tracer-02 from Nanoluc-fused BRD9 bromodomain (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD7 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50619065(CHEMBL5412877)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD9 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed