BDBM50618669 CHEMBL5396285

SMILES CCCCN([C@H](C(C)C)C(O)=O)S(=O)(=O)c1ccc(cc1)-c1nc(no1)-c1ccc(C)s1

InChI Key InChIKey=TWUOGBAWSSAHQE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50618669   

Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 547nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 212nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed