BDBM50618609 CHEMBL5438800

SMILES CNc1ncc2cc(-c3cc(Br)ccc3Cl)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1

InChI Key InChIKey=QHGBYRNKDSLEHW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50618609   

TargetSerine/threonine-protein kinase SIK1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618609(CHEMBL5438800)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full length NanoLuc fused SIK1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618609(CHEMBL5438800)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of full length NanoLuc fused SIK2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618609(CHEMBL5438800)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length NanoLuc fused SIK3 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed