BDBM50618270 CHEMBL5436239

SMILES NC(Cc1ccc(=O)n(O)c1)C(O)=O

InChI Key InChIKey=KGJHRVKISXOVEV-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50618270   

TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataKi:  4.20E+4nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed