BDBM50618174 CHEMBL5427713

SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCC(=O)OCc2c(no[n+]2[O-])-c2ccccc2)c(C)c1

InChI Key InChIKey=SUMJFWHWPZJWDQ-UHFFFAOYSA-N

Data  8 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50618174   

TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of BRD2 bromodomain 1 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BRD2 bromodomain 2 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BRD3 bromodomain 1 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BRD3 bromodomain 2 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 820nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BRDT bromodomain 1 (unknown origin) by Alphascreen based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataKd:  7.43E+3nMAssay Description:Binding affinity to BRD2 BD1 (unknown origin) by thermal denaturation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataKd:  1.75E+4nMAssay Description:Binding affinity to BRD2 BD2 (unknown origin) by thermal denaturation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataKd:  419nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by thermal denaturation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618174(CHEMBL5427713)
Affinity DataKd:  686nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) by thermal denaturation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed